產品詳情
Cat#：194P32
序列（三字母）：H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH trifluoroacetate salt
序列（單字母）：SFLLRNPNDKYEPF
類似名：Thrombin Receptor Activator Peptide 14, PAR-1 (1-14) (human), Proteinase Activated Receptor 1 (1-14) (human), Thrombin Receptor (1-14) (human), Coagulation Factor II Receptor (1-14) (human), Thrombin Related Peptide
分子式：C??H???N??O??
分子量：1739.95
CAS#：137339-65-2
合成方法：Synthetic
存儲條件：-20 ± 5 °C
應用：Cardiovascular System & Diseases|
Hematology
描述：Cloning and expression of a functional human thrombin receptor have revealed a protein with seven transmembrane domains and a large extracellular amino-terminal extension. Thrombin cleaves within this extension, thereby creating a new receptor amino-terminus that functions as a tethered ligand and activates the receptor. A 14-amino acid peptide mimicking this new amino-terminus has been found to be a potent thrombin receptor activator as well as an effective agonist for platelet activation.
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